An Iranian airliner en route to neighbouring Armenia has crashed into farmland northwest of Tehran killing all 168 people on board.
It is the worst air disaster in Iran in recent years.
Witnesses said the plane exploded after it dropped out of the sky on Wednesday. Television images showed a vast crater at the disaster site littered with debris of plane parts, shoes and clothes.
"All people aboard... the crashed plane are dead. The plane had 153 passengers and 15 crew members," said Mohammad Reza Montazer Khorasan, the head of the disaster management centre at Iran's health ministry.
The Caspian Airlines Tupolev crashed near a village outside the city of Qazvin shortly after takeoff from Tehran's international Imam Khomeini airport.
The passengers included 10 members of Iran's junior national judo team.
"The aircraft all of a sudden fell out of the sky and exploded on impact, where you see the crater," a witness told Iran's English-language Press TV from the crash site near the village of Janat Abad.
Armenian television reported that the crash was caused by an engine fire, without giving any sources.
Iran's ISNA news agency also quoted a local police officer as saying that some witnesses had reported that the plane was on fire mid-air.
Iran, which has been under years of international sanctions, has suffered a number of aviation disasters over the past decade but Wednesday's crash is the worst for many years.
"The plane took off from the Imam Khomeini airport at 11:33 am (4.03pm EST) and 16 minutes later it disappeared off the radar and then it crashed," said civil aviation spokesman Reza Jafarzadeh.
"We cannot confirm anything more before we receive additional information from the team that we despatched at the crash site."
Iranian state television's website quoted Ahmad Momeni, managing director of Iran's airport authority, as saying that the last conversation between the pilot and the ground was "normal and did not indicate any technical glitch."
Another witness was quoted by ISNA as saying the plane had circled for sometime for a possible landing before it crashed in a wheat farm.
President Mahmoud Ahmadinejad has ordered the transport ministry to launch a probe into the disaster.
"The passenger plane was completed destroyed and the wreckage was scattered everywhere," the state news agency IRNA quoted Qazvin police chief Masoud Jafari Nasab as saying.
Ahmad Mousavi, secretary general of the Iranian Red Crescent, said: "The massive explosion caused severe burns. We were unable to do anything."
In December 2005, a total of 108 people were killed when a Lockheed C-130 transport plane crashed into a foot of a high-rise housing block outside Tehran.
Twenty-nine people were killed in September 2006 when an airliner came off the runway after landing in the eastern city of Mashhad and burst into flames.
In November that year, a military plane crashed on takeoff at Tehran's Mehrabad airport, killing all 39 people on board, including 30 members of the elite Revolutionary Guards.
Iran's civil and military fleet is made up of ancient aircraft in very poor condition due to their age and lack of maintenance. The Iranian regime is barred by sanctions from buying American Boeing planes or European Airbus aircraft when they include a significant number of US parts.
Caspian Airlines was established in 1992. Its website said it operates more than 50 regular and numerous charter flights each week between Iranian cities and international flights to Hungary, the United Arab Emirates, Syria, Ukraine, Armenia, Belarus and Turkey.
Landlocked Armenia has been seeking closer ties with Iran because of an economic blockade imposed by neighbours Azerbaijan and traditional foe Turkey.
The Islamic republic is home to hundreds of thousands of Armenians and a string of historically important churches of the country's Gregorian rite.
Washington has raised concerns about the warming ties, with US officials saying in June that Armenia should join in international sanctions aimed at persuading Iran to halt sensitive nuclear work.
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